The Binding of Isaac

The Binding of Isaac

Total Views:
476,967,560
Total Channels:
12,604
Total Videos:
75,127
Total Duration:
2433:01:59:27
Mean Duration:
46:38
Median Duration:
31:55



Latest Let's Play Channel Activity for The Binding of Isaac


This list represents YouTube let's play channels for The Binding of Isaac based on recent uploads. This only includes channels that have created let's play videos. Channels are checked for new videos via the YouTube API every 4 hours. Any channel that uploads a new let's play for The Binding of Isaac will appear at the top of the list.


PublishedChannelSubscribersLatest Video
1 day agoGermany Gorbinski666791The Binding of Isaac Repentance 3.0 ✿ 247 ✿ Let's Play German Deutsch55:02
4 days ago omnipian277Omnipian Plays The Binding of Isaac - Part 26252:06
4 days ago DrowsyZuluPlayz1,050Luck foot is op | binding of Isaac lets play35:28
2024-04-28United States KAIRO188Kairo Plays: The Binding of Isaac Repentance19:32
2024-04-27Poland Ephrio721Isaac kontra Chub1:02
2024-04-26 ExaggeratedElegy2,760Let's Play The Binding of Isaac: Pay 2 Play.35:45
2024-04-25 Daniel Cornwall23Lets Play the Binding of Isaac Part 182(That Lucky Old Shit)1:36:16
2024-02-23Germany GameJam - Englisch324Ich liebe es da es ein spannender Run wird! in The Binding of Isaac | Let's play German / Deutsch2:08:08
2024-02-11United States Emerald Masters110,000Shadow plays The Binding Of Isaac!15:22
2024-02-11 Indelacio.co.uk : Lets Plays and Game Reviews425Ziggurat Single Play Doom meets The Binding Of Isaac With Wands #ziggurat #singleplay #rotuelike3:29:46
2024-02-10 LeooBruu125👊Si me golpean cambio de juego👊11:30
2024-01-27 TheEmero55,900Let's Play The Binding of Isaac [s2e2] - Alles wie immer32:38
2024-01-18Spain RetroGosus2,80010 JUEGOS en los que PUEDES MORIR de UN SOLO GOLPE8:26
2024-01-18France CedSphere393💩 ON SE FAIS UNE DERNIÈRE RUN ? | The Binding Of Isaac (05)3:10:15
2024-01-17United States Nicky Plays Best112🔴 LIVE - [THE BINDING OF ISAAC] gameplay! chat! coop! playthrough!1:07:43
2023-12-30 Elite4Stephan116The Binding of Isaac: Bethany Plays Ep 3829:54
2023-12-29United Kingdom shirlierox8,240The Binding of Isaac but with magic in - Magicraft game first look15:39
2023-12-22United States WaybackGuy245EVE PLAY ! The Binding Of Isaac [FLASH] WRATH OF THE LAMB (First Play) WAYBACKGUY50:54
2023-11-11 0Nogs121One Must Imagine Isaac Happy.. #shorts #TBoI #sisyphus #trend #painful #WHYYYY #bruh #moment #Helpme1:00
2023-11-08Spain ErSeFiRoX6,540DARK GEMS // PLATINO FACIL3:24
2023-11-03Canada Dean Lofi Plays1,680Magicraft - NEW Super Fun Spell Crafting Roguelike RPG!!!28:07
2023-10-22Chile Black_Stark2344Fast-paced Real Time Deckbuilder Roguelite | RUNGORE - Part 125:51
2023-10-08Germany WuTanfall LP1,060Gegner weg weinen #1 | Let's Play [German]28:25
2023-09-21Chile Tipooh11,100CUANTAS HORAS le tienes al ISAAC? #tboi #thebindingofisaac #pepiig #elpepig0:06
2023-09-04United States LoneWolf Gaming9the binding of isaac full game25:46
2023-08-28Ireland Moth Girl Hina819It Dies [VTUBER]2:29:41
2023-08-25 Guy Man Lad144The Binding Of Isaac [Road To Dead God] - Part 41: Holy Water Helper27:54
2023-08-10 XorlGameplay44¡¡ME ENFRENTO A TODOS LOS BOSSES EN UNA SALA CON UNA MALA BUILD!! let's play the binding of isaac21:02
2023-07-27Brazil Sabresenn768Viagem no tempo com @AlphaCoda Binding Of Isaac wrath of the lamb (PT - BR) - #SLA42:30
2023-06-25United States Kyzers Game Zone58,800Basement Dweller - Kyzer Plays The Binding of Isaac - Part 1 [K.A.T.V.]26:51
2023-06-11 Slurm Durm Darkskel299Darkskel Plays The Binding Of Isaac Episode 6 - Well I think I am Going To Die19:39
2023-06-06United States bobfleadip3,040AGNB Plays: The Binding of Isaac - Episode 1642:26:26
2023-05-31 Anixxie1First time Playthrough43:27
2023-05-30United Kingdom TophuNugget4,210i'm a greedy rat54:10
2023-05-26United States Fuerutar84Great Steam Library Playthrough: Episode 591:10:03
2023-05-11 Lunar D8348lets play Cavity Busters blind part 1 who needs a tutorial21:42
2023-05-06United States Meeshawe28Sweet Merciful Buddha Help! (Binding of Isaac)1:36:00
2023-04-09 paddyator1Paddy plays The binding of Isaac2:27:07
2023-04-09 GamesWithSylle74Lets play Binding of Issac Wrath of the lamb - Episode 819:40
2023-04-07Germany Zathuria72MOTHER MUST DIE! 🩸 || The Binding of Isaac Part 312:33
2023-04-03 Bear Squire1,740My 2nd Playthrough of the Binding of Isaac After Years of Not Playing27:51
2023-03-22United States philcube614STARTING THE BINDING OF ISAAC FROM THE BEGINNING (TIPS AND EXPLANATIONS) LETS PLAY PART 11:37:45
2023-03-20Spain Olsilver1,340Olplatita vs Rom de The Binding of Isaac0:51
2023-03-06United States HoTPoTaToisLive715🔴 LIVE! The Binding of Isaac Noob playthrough - Playing with Viewers with Parsec!3:24:28
2023-03-04 NotKale11An AI plays The Binding Of Isaac8:19
2023-03-04Ukraine IvanK° Play1,300ПРОХОЖДЕНИЕ || I.RULE: НОВЫЕ ЗАСРАНЦЫ || #2 || Иванко Плей35:31
2023-02-08 Isaacorus14Holy Card could help... (Binding Of Isaac)0:19
2023-02-01 TheToppestRamen0TheToppestRamen Plays: The Binding of Isaac, The Road to Unlocks, Part 131:51
2023-01-19United States Buttons N Blunts1,340Binding of Isaac First Playthrough #bindingofisaac0:59
2023-01-15 MattSlash Gaming134Sunday Funday - Medical Malpractice!!!56:56
2022-12-07United States NOZUTO8Let's Play - The Binding of Isaac - Episode 3 [Rebirth]1:54:05
2022-11-28 Astrosmash Gaming161Let's Play Binding of Isaac... on a Monday. Sheesh.7:22
2022-11-28 Easy Mr.Strange155BROTATO - Der Masochist, absolute Damage Eskalation [E07]32:22
2022-10-21United Kingdom TheTurtleMelon12,200BEING A TRUE PACIFIST!! - Brotato Early Access - Part 832:57
2022-10-16Germany melikaDüstermärchen282Vampire Survivors und The Binding of Isaac haben ein Kind | Brotato40:11
2022-09-24Italy Gingerino022Daily Run - 23 Settembre 2022 - The Binding of Isaac - #124 su 365 Challenge35:18
2022-09-17United States Dinklez1,430"Good" at The Binding of Isaac: The Alphabet Challenge12:36
2022-09-15Canada Meruru13,000【The Binding of Isaac】guerilla! ♡ help me wake up for my errands c:1:16:56
2022-09-05United States Tranquility22The Binding of Isaac - Episode 2 Playthrough + Commentary26:43
2022-09-03United States ThatRabbitGuyS4,980The Binding Of Isaac Episode 4 Play Through!39:17
2022-08-29United States TimAndTex273Jerry Seinfeld Plays The Binding of Isaac40:55
2022-08-28 isaacfan1119The Binding Of Isaac Lets Play #8 New save file!26:36
2022-08-19Malaysia Chris D' L5,56050 Hardest Games in PS Vita (Alphabet Order)9:30
2022-08-15 forgottenGaming2Let's Play the Binding of Isaac EP 1:Mom?25:50
2022-08-09 Liz Tries62The Neighborhood Watch Weekend to Help IRC!2:05:58
2022-08-07United Kingdom Dan Does16,600How to Make Lots of The Binding of Isaac Sculpts!5:57
2022-08-03United States Cryptidiots263Not Indy completely discrediting Kai's helpfulness! #Cryptidiots #bindingofisaac #gaming #letsplay0:24
2022-08-02 Doctor MGW12358The Binding Of Isaac ; Help From Big Brother7:53
2022-07-27United States jasonsgroovemachine299Let's Play Binding Of Isaac57:11
2022-07-21 Legavindary Clips10ARGONAUT PLAYS THE BINDING OF ISAAC... again?2:21:39
2022-07-05United Kingdom Game N Chat , Lill86🔴Binding of Isaac, Repentance #30 Lill 🤗 Quest for Tainted Isaac2:22:50
2022-06-14Canada Tom Vs Everything8,280New Update For Potato Shooter! | Lets Plays Brotato Demo12:20
2022-06-12United States The Defective Butcher489LET'S GET HELLA SCARED LIVE!!! (Dungeon Nightmares 3, SCP Unity, The Binding of Isaac)2:10:14
2022-06-11 LostContext Plays55Wheel of Shame: Steam Backlog Edition, Ep. #6 | The Binding of Isaac | LostContext Plays24:48
2022-05-16Switzerland Corbel1,270Détente: The Binding Of Isaac #9 [Let's Play FR]1:21:29
2022-05-11Brazil YTQUIKJOGA309PERDI A MONETIZACAO the binding of isaac Ao som de T.i. & Rihana2:31
2022-05-04 YourLilBro178Rooki plays Binding of Isaac Part 104:03:13
2022-05-03 marcx world189The binding of isaac; little sis playthrough26:13
2022-05-03Germany Rob Flynn1,300The Binding Of Isaac: Wrath Of The Lamb - Episode 57:39:28
2022-04-20 Whinot Gaming17The Binding Of Isaac Ep.7 Beating MOM!1:08:57
2022-04-19United States Olexa151,000IS THIS THE NEXT BINDING OF ISAAC? | Revita 1.0 Full Release56:24
2022-04-09Germany Wolverous98,200The Binding Of Isaac Freunde AUFGEPASST13:47
2022-03-09Germany CyberNightmare1,040I Rule Alpha Gameplay Deutsch Part 3 // The Binding of Isaac + Plants vs. Zombies Fangame29:12
2022-02-28Brazil Force74,500O BABY QUE COPIA OS OUTROS - I.Rule Alpha - #5 PTBR22:37
2022-02-20Spain el tema que yo elija9I.RULE alPhA1:19:49
2022-02-14United States OmniPie 245,000Beating All Three Bosses! I.Rule Gameplay I Rule!13:41
2022-02-07 TraBombVods202The Binding Of Isaac Playthrough: File 3 ep.21 Waka Waka Challenge, Darkness Falls Challenge, Cain,1:15:17
2022-01-17 ScrubGaming0The Binding of Isaac - when you have a little too much help beating Satan0:30
2021-12-07 Vladimir475719Let's Play The Binding of Isaac Ep6 : A Perfect Run29:47
2021-11-23 DerpSkelly78Hallppp!! Mum Tryna Kill Meee!!!! | The Binding of Isaac #536:09
2021-10-14United Kingdom Kino_Plays29Kino-Plays: The Binding of Isaac - 13/10/21 - 21:02:32
2021-10-12Germany Yolandi und Hieooo zocken1,130let's play THE BINDING OF ISAAC ♦ #S02E13 ♦ Aller guten Dinge sind drei [ENDE]24:25
2021-09-29 Mega Radar248Deer plays smash with his chat. oh ya and some binding of isaac after birth.4:06:45
2021-09-27United Kingdom OwlTowel2,090[Super OwlPlays] - The Binding of Isaac (Flash Version): “The Eternal Suffering”29:58
2021-09-10 Señor Caracoles World64The Binding of Isaac guía + lore EP 16 - ¡Disculpen las molestias!15:12
2021-08-28United States zombiewarrior88210Lets Play The Binding Og Isaac Part 125:47
2021-08-22 Darkskel17Darkskel Plays The Binding Of Isaac Episode 26 With Commentary - Help us win another one!29:22
2021-07-08 ItsNotDuckiii26Duckii Plays - Friday Night Funkin' The Binding of Isaac Mod6:56
2021-07-06Saudi Arabia Z9GN2,150INTO THE COLD (DEMO) - GAMEPLAY12:16
2021-06-14United States Team Nova290Isaac episode 1 - Bad plays23:01