| 2 days ago |  AbeClancy | Two Esaus Are Better Than One - #345 - Abe Clancy Plays: The Binding of Isaac Repentance | 1:02:10 | 80 |
| 2 days ago | SolidSun | The Forgotten vs. Mother | The Binding of Isaac: Repentance [272] | 44:33 | 1 |
| 3 days ago | AbeClancy | Spider Machine Gun - #344 - Abe Clancy Plays: The Binding of Isaac Repentance | 1:20:08 | 171 |
| 3 days ago |  WuTanfall LP | Trottel + Bug = Unfall #letsplay | 0:31 | 405 |
| 3 days ago | SolidSun | The Forgotten vs. ??? + Delirium | The Binding of Isaac: Repentance [271] | 1:06:30 | 7 |
| 4 days ago | AbeClancy | Fly Guy - #343 - Abe Clancy Plays: The Binding of Isaac Repentance | 1:36:52 | 177 |
| 4 days ago | SolidSun | The Forgotten vs. ??? + Mega Satan + Delirium | The Binding of Isaac: Repentance [270] | 1:14:53 | 8 |
| 5 days ago |  Mickanondorf | Let's play - The Binding of Isaac Repentance - Quelques défis - Partie 1 | 23:34 | 11 |
| 6 days ago | bisnap | Isaac to help me recover from surgery | 2:41:04 | 1,297 |
| 6 days ago | Bumm36 | Lets Play The Binding of Isaac Repentance 04 (Blind, german, PS4, HD) | 36:58 | 7 |
| 6 days ago | WolfBiteLP | - Part 5 | Live (Let's Play Voice of Cards German) | 1:03:36 | 1 |
| 2024-05-18 | AbeClancy | 3RR0R - #341 - Abe Clancy Plays: The Binding of Isaac Repentance | 46:53 | 147 |
| 2024-05-17 | GMSryBut | Onan's Streak - Afterbirth Challenge #29 - The Binding of Isaac Repentance | 41:02 | 9 |
| 2024-05-16 | SolidSun | The Forgotten vs. Hush + ??? | The Binding of Isaac: Repentance [269] | 51:55 | 4 |
| 2024-05-16 | AbeClancy | Splash Damage - #339 - Abe Clancy Plays: The Binding of Isaac Repentance | 1:04:49 | 133 |
| 2024-05-16 | GMSryBut | PRIDE DAY! - Afterbirth Challenge #28 - The Binding of Isaac Repentance | 31:00 | 8 |
| 2024-05-15 | SolidSun | The Forgotten vs. Boss Rush + ??? | The Binding of Isaac: Repentance [268] | 55:02 | 5 |
| 2024-05-15 | GMSryBut | BRAINS! - Afterbirth Challenge #27 - The Binding of Isaac Repentance | 37:30 | 7 |
| 2024-05-15 | Bumm36 | Lets Play The Binding of Isaac Repentance 02 (Blind, german, PS4, HD) | 1:01:39 | 11 |
| 2024-05-14 | SolidSun | Apollyon vs. Ultra Greed | The Binding of Isaac: Repentance [267] | 39:18 | 2 |
| 2024-05-14 | GMSryBut | I RULE - Afterbirth Challenge #26 - The Binding of Isaac Repentance | 42:30 | 2 |
| 2024-05-13 | SolidSun | Apollyon vs. Boss Rush + Hush + ??? | The Binding of Isaac: Repentance [266] | 46:21 | 10 |
| 2024-05-13 | GMSryBut | Have a Heart - Afterbirth Challenge #25 - The Binding of Isaac Repentance | 27:42 | 12 |
| 2024-05-12 | PlatinumDom | LIVE! Noob Plays Binding Of Isaac Duo W/ @stellar2blue | 2:39:13 | 142 |
| 2024-05-12 | GMSryBut | Pay to Play - Afterbirth Challenge #24 - The Binding of Isaac Repentance | 32:11 | 8 |
| 2024-05-12 | WolfBiteLP | - Part 4 | Live (Let's Play Voice of Cards German) | 1:02:24 | 7 |
| 2024-05-11 | GMSryBut | Blue Bomber - Afterbirth Challenge #23 - The Binding of Isaac Repentance | 22:34 | 9 |
| 2024-05-10 | GMSryBut | SPEED! - Afterbirth Challenge #22 - The Binding of Isaac Repentance | 16:54 | 11 |
| 2024-05-09 | GMSryBut | XXXXXXXXL - Afterbirth Challenge #21 - The Binding of Isaac Repentance | 1:07:03 | 14 |
| 2024-05-08 | Joey Flex | HOW TO UNLOCK TAINTED AZAZEL! CRAZY OP DMG! MrJoeGames Plays The Binding of Isaac Repentance! EP 64! | 50:16 | 61 |
| 2024-05-08 | GrennehLeVrai | Je l'ai ENFIN eu!!! | 11:58 | 1,852 |
| 2024-05-08 | GMSryBut | Purist - Rebirth Challenge #20 - The Binding of Isaac Repentance | 44:49 | 19 |
| 2024-05-07 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 250 ✿ Let's Play German Deutsch | 45:13 | 50 |
| 2024-05-07 | SolidSun | Apollyon vs. Mother | The Binding of Isaac: Repentance [265] | 57:46 | 12 |
| 2024-05-07 | GMSryBut | The Host - Rebirth Challenge #18 - The Binding of Isaac Repentance | 27:53 | 6 |
| 2024-05-06 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 249 ✿ Let's Play German Deutsch | 48:42 | 38 |
| 2024-05-06 | SolidSun | Keeper vs. Ultra Greed | The Binding of Isaac: Repentance [264] | 28:46 | 11 |
| 2024-05-06 | GMSryBut | Waka Waka - Rebirth Challenge #17 - The Binding of Isaac Repentance | 37:02 | 9 |
| 2024-05-05 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 248 ✿ Let's Play German Deutsch | 32:30 | 31 |
| 2024-05-05 | GMSryBut | Computer Savvy - Rebirth Challenge #16 - The Binding of Isaac Repentance | 17:30 | 4 |
| 2024-05-05 | WolfBiteLP | Die neue Insel - Part 3 | Live (Let's Play Voice of Cards German) | 50:46 | 5 |
| 2024-05-05 |  BLUE ISLAND | YIN SALAH PILIH LAWAN AUTO DISAYURIN ALPHA MOBILE LEGENDS BANG BANG #mobilelegends #mlbb | 0:30 | 464 |
| 2024-05-05 | BLUE ISLAND | ALPHA MENJADI MAN OF THE MATCH DISINI SEBAGAI JUNGLER MOBILE LEGENDS BANG BANG | 24:35 | 113 |
| 2024-05-04 | Minakata Gaming | The lighting at that thigh tho... brrrrrr (Japanese voice) | 1:09:50 | 235 |
| 2024-05-04 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 247 ✿ Let's Play German Deutsch | 55:02 | 43 |
| 2024-05-04 | Degenerate Plays | The Censorship Problem - Stellar Blade : Part 5 | 29:34 | 781 |
| 2024-05-04 | GMSryBut | Slow Roll - Rebirth Challenge #15 - The Binding of Isaac Repentance | 21:30 | 3 |
| 2024-05-04 | Minakata Gaming | So nice... I am out of idea for Title so i just trying to clickbait you (Japanese voice) | 3:58:22 | 57 |
| 2024-05-03 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 246 ✿ Let's Play German Deutsch | 31:30 | 121 |
| 2024-05-03 | SolidSun | Keeper vs. Boss Rush + Hush + ??? | The Binding of Isaac: Repentance [263] | 34:51 | 4 |
| 2024-05-03 | raylene | Raylene's FINAL FANTASY 7 REBIRTH | (Part Thirteen) First Time Playthrough | 58:13 | 157 |
| 2024-05-03 |  Spiff | A game so good I lost ALL my hair | 35:26 | 23 |
| 2024-05-03 | GMSryBut | It's in the Cards - Rebirth Challenge #14 - The Binding of Isaac Repentance | 25:15 | 14 |
| 2024-05-03 |  Vali S | Sta bine pe posterior#stellarblade #eve #evesterllarblade #ps4 #ps5 #ps5gameplay #playstation | 0:18 | 3,219 |
| 2024-05-02 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 245 ✿ Let's Play German Deutsch | 1:07:11 | 48 |
| 2024-05-02 | SolidSun | Keeper vs. Mother | The Binding of Isaac: Repentance [262] | 53:44 | 8 |
| 2024-05-02 | GMSryBut | Beans! - Rebirth Challenge #13 - The Binding of Isaac Repentance | 18:51 | 8 |
| 2024-05-01 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 244 ✿ Let's Play German Deutsch | 1:31:00 | 42 |
| 2024-05-01 | SolidSun | Keeper vs. Mega Satan | The Binding of Isaac: Repentance [261] | 1:08:11 | 4 |
| 2024-05-01 | Degenerate Plays | Every Game Needs Easy Mode? - Stellar Blade : Part 4 | 25:56 | 520 |
| 2024-05-01 | GMSryBut | When Life Gives You Lemons - Challenge #12 - The Binding of Isaac Repentance | 24:42 | 8 |
| 2024-05-01 | Aika Morii | [VOD] Shantae and The Seven Sirens - On secours les demi-génies ! - LET'S PLAY- #2 | 4:34:45 | 13 |
| 2024-04-30 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 243 ✿ Let's Play German Deutsch | 50:05 | 46 |
| 2024-04-30 | SolidSun | Run 260 | Lilith vs. Ultra Greed | The Binding of Isaac: Repentance | 33:06 | 4 |
| 2024-04-30 | Sinvicta | When #isaac plays nice?! - The Binding Of Isaac: Repentance #1034 #isaacrepentance #bindingofisaac | 1:12:59 | 47,510 |
| 2024-04-30 | GMSryBut | Glass Cannon - Challenge #11 - The Binding of Isaac Repentance | 41:27 | 5 |
| 2024-04-29 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 242 ✿ Let's Play German Deutsch | 57:40 | 49 |
| 2024-04-29 | SolidSun | Run 259 | Lilith vs. Boss Rush + Hush + ??? | The Binding of Isaac: Repentance | 47:40 | 6 |
| 2024-04-29 | GMSryBut | The Family Man - Challenge #19 - The Binding of Isaac Repentance | 43:06 | 6 |
| 2024-04-28 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 241 ✿ Let's Play German Deutsch | 1:30:28 | 62 |
| 2024-04-28 | WolfBiteLP | Der Naturgeist - Part 2 | Live (Let's Play Voice of Cards German) | 1:51:58 | 6 |
| 2024-04-28 | GMSryBut | Höllenfeuer Party #srylightshighbut #shorts #overpowered | 0:44 | 11 |
| 2024-04-28 | KAIRO | Kairo Plays: The Binding of Isaac Repentance | 19:32 | 3 |
| 2024-04-27 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 240 ✿ Let's Play German Deutsch | 43:38 | 30 |
| 2024-04-27 |  Tamil Nerdy Gamer | Best games for Low End PC #tamilnerdygamer #tamilpcgaming #tamilgaming | 0:28 | 525 |
| 2024-04-26 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 239 ✿ Let's Play German Deutsch | 1:17:32 | 38 |
| 2024-04-25 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 238 ✿ Let's Play German Deutsch | 42:39 | 37 |
| 2024-04-25 | GMSryBut | Cursed! - Challenge #10 - The Binding of Isaac Repentance | 19:00 | 14 |
| 2024-04-25 | Irina Ch. 熊井 いりな | Irina plays The Binding of Isaac (she's a pro!) | 2:18:14 | 63 |
| 2024-04-24 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 237 ✿ Let's Play German Deutsch | 28:16 | 46 |
| 2024-04-24 | GMSryBut | Demo Man - Challenge #9 - The Binding of Isaac Repentance | 32:39 | 8 |
| 2024-04-23 |  lives do rik | um Isaac pra ficar calminho | donatona - dia 3 !fala !pix !palpite | 3:03:40 | 1,302 |
| 2024-04-23 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 236 ✿ Let's Play German Deutsch | 1:15:52 | 50 |
| 2024-04-23 |  dngplays | Vamos a Jugar The Binding of Isaac: Repentance - #48 - Desbloqueamos a Tainted Jacob | 1:32:53 | 8 |
| 2024-04-23 | GMSryBut | Cat Got Your Tongue - Challenge #8 - The Binding of Isaac Repentance | 36:52 | 13 |
| 2024-04-23 | GMSryBut | Random OP Run #shorts #srylightshighbut #thebindingofisaac | 0:53 | 122 |
| 2024-04-22 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 235 ✿ Let's Play German Deutsch | 1:01:49 | 31 |
| 2024-04-22 | SolidSun | Run 258 | Lilith vs. Mother | The Binding of Isaac: Repentance | 46:06 | 9 |
| 2024-04-22 | GMSryBut | Suicide King - Challenge #7 - The Binding of Isaac Repentance | 29:34 | 6 |
| 2024-04-21 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 234 ✿ Let's Play German Deutsch | 31:01 | 33 |
| 2024-04-21 | GMSryBut | Solar System - Challenge #6 - The Binding of Isaac Repentance | 25:13 | 2 |
| 2024-04-21 | WolfBiteLP | Abwesende Miko - Part 1 | Live (Let's Play Voice of Cards German) | 43:14 | 0 |
| 2024-04-21 | Joey Flex | The BEAST has been SLAIN! Apollyon SO GOOD! MrJoeGames Plays The Binding of Isaac Repentance! EP 63! | 49:11 | 49 |
| 2024-04-20 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 233 ✿ Let's Play German Deutsch | 53:36 | 45 |
| 2024-04-20 | GMSryBut | The Tank - Challenge #5 - The Binding of Isaac Repentance | 33:21 | 2 |
| 2024-04-19 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 232 ✿ Let's Play German Deutsch | 37:57 | 32 |
| 2024-04-18 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 231 ✿ Let's Play German Deutsch | 43:05 | 35 |
| 2024-04-18 | bobfleadip | AGNB Plays: The Binding of Isaac Repentance - Episode 272 | 2:36:06 | 13 |
| 2024-04-18 | GrennehLeVrai | Je veux GULP par pitié... | 13:09 | 1,247 |
| 2024-04-17 | Gorbinski666 | The Binding of Isaac Repentance 3.0 ✿ 230 ✿ Let's Play German Deutsch | 47:49 | 43 |
