| 101. |  ころんの実況【すとぷり】 | 527,817 | すとぷり様には本当にお世話になっております。【ころん】すとぷり | 12:55 |
| 102. |  DPadGamer | 526,325 | A Fever Dream of Easter Eggs in Tomodachi Life - DPadGamer | 15:41 |
| 103. |  Thomas Game Docs | 522,751 | The Nintendo game rated 18+ | 6:31 |
| 104. | Smashed Tomatoes | 481,876 | Clown Dreaming of Tomodachi Sequel Reacts to Nintendo Direct | 1:28:25 |
| 105. | AceAngelPrincess | 457,882 | "I Hope You're Cool with" Me Dating Your Crush - Tomodachi Life | 0:36 |
| 106. | Nintendo Hero | 454,449 | Tomodachi Life 2 Please Nintendo | 0:42 |
| 107. | BanditGames | 453,676 | All Bosses EXPLAINED in Zelda: Ocarina of Time | 18:57 |
| 108. |  Eleonora Olivieri | 421,944 | Tomodachi Life in Real Life 2 (Love confessions) ITA [SUB ENG] | 2:26 |
| 109. | Thinknoodles | 421,768 | INTRODUCING JAMES!! | Tomodachi Life | Fan Choice Favorite | 22:04 |
| 110. | miharasan | 417,852 | 『はまぐち まさる』さん、撮ったどぉ！ | 0:51 |
| 111. |  Kirbendo - Let’s Play | 407,254 | Quand t'oublie l'anniversaire de ton pote en live... | 0:25 |
| 112. | OcariKnights | 396,065 | Amour chimérique - Tomodachi Life | 1:03 |
| 113. |  TheGame Boys | 341,655 | Tomodachi Life OST; Ranking Popularity | 2:15 |
| 114. | 右折禁止JAPAN | 334,564 | 【おめでとう】大谷翔平の結婚を友達コレクションで祝福しよう【トモダチコレクション新生活】 | 19:38 |
| 115. | Ygeth | 325,583 | Tomodachi Life 14 [Let's Play FR]- La naissance de fin ! | 29:38 |
| 116. |  Laowu老吳 | 324,496 | 美版《New 3DS XL怪物猎人4 同捆套装》開箱影片[老吳] | 12:39 |
| 117. | 笹木咲 / Sasaki Saku | 324,041 | 【トモダチコレクション】住民達と遊ぶ。歌を作ったら歌詞がひどすぎた。【笹木咲/にじさんじ】 | 1:49:50 |
| 118. | Polygon | 312,218 | Tomodachi Survivor, Episode 4: Augmented Reality | 20:55 |
| 119. | AquaTwist | 294,017 | Find Mii II Main Quest Tutorial (Streetpass Live 2 Preview) | 2:26 |
| 120. | Akram BRZ | 287,457 | la CARTOUCHE MAUDITE de TOMODACHI LIFE... #nintendo #shorts | 0:18 |
| 121. | Salty's Video Dump | 286,195 | Tomodachi Life (STREAM 9) - Salty | 1:33:51 |
| 122. |  Tesla | 280,241 | STEALING From EVERYONE - Rust Duo | 51:18 |
| 123. | Jack Sorrell | 279,870 | How to Homebrew a Nintendo 3DS 11.4 | 9:48 |
| 124. | DidYouKnowGaming | 272,601 | Nintendo Controversies - Did You Know Gaming? Ft. Greg | 12:29 |
| 125. |  Wilbo | 271,418 | TOMODACHI LIFE IS TERUG!? | 11:01 |
| 126. |  ESPALTeam | 270,560 | Podcast ESPAL3DS: Temporada 7 - Capítulo 35 | 1:28:17 |
| 127. |  Domtendo | 267,342 | Let's Show Tomodachi Life: So trashig, dass es schon wieder cool ist | 31:58 |
| 128. | LRLF_GAMES _(UNDERTALE) AU | 265,266 | れるりふの息子が成長していく姿が泣ける…?【トモダチコレクション新生活】part19 | 23:51 |
| 129. | PLAYERINSIDUE | 265,256 | VOLTI INQUIETANTI! Tomodachi Life | 5:46 |
| 130. | NintendoAU | 260,715 | Episode 3 - Tomodachi Life - Dami gets the word out! | 1:28 |
| 131. | Captain Southbird | 256,882 | Darling, Please Get Over Yourself [TLAI #69] | 22:05 |
| 132. | DazzaBound | 250,847 | Tomodachi Life :: 21 - Miis In Space! ~FINALE~ | 21:54 |
| 133. | NookNews | 249,491 | The Return of Tomodachi Life | 10:39 |
| 134. | Luna's Soundtrack | 247,708 | Clothes Shop - Tomodachi Life Soundtrack | 15:01 |
| 135. | kaiangel7 | 231,845 | How To Convert A 3DS CIA To A Playable 3DS File - Citra Emulator | 7:30 |
| 136. | ShadySideGaming | 225,859 | Let's Play Tomodachi Life - Ep 11 "Welcome Luke and Julie!" | 16:13 |
| 137. | BADASS GAMING | 218,048 | HOW DID YOU DIE?!?! (So This Is Why We Can't Have Nice Things) FUNNY!!! | 10:56 |
| 138. | JEUXACTU | 212,325 | Kev Adams pécho sur Tomodachi Life ! | 0:31 |
| 139. | Alpharad LIVE | 212,255 | Turning my Friends into Miis | 34:13 |
| 140. | Sylkeka | 212,137 | Tomodachi | T2 | Ep104 | El pañal ya tiene su dia | 25:52 |
| 141. | IGN | 211,654 | 3 Predictions for Nintendo's First Smartphone Game | 4:59 |
| 142. | Vappyvap Backup | 208,925 | [Vinesauce] Vinny - Tomodachi Life (part 31) + Art! | 1:47:12 |
| 143. | Monsieur Plouf | 191,449 | Chroniques de Mr. Plouf #39 - Tomodachi Life | 7:05 |
| 144. | s,,,,,, | 190,259 | The Mii Iceberg Explained - G4tor | 47:07 |
| 145. | SupaDaBloopa | 189,409 | The Time I (accidentally) Fooled an Entire Gaming Community | Tomodachi Life DX | 7:25 |
| 146. | Arlo | 186,997 | Let's Predict Nintendo's 2023! | 23:19 |
| 147. | Cornel | 184,989 | DAS GROßE FINALE! DAS ENDE VON TOMODACHI LIFE! ▪ Tomodachi Life #038 | 6:46 |
| 148. | Nintendo België | 184,341 | Miitopia - Beleef een groots avontuur met je vrienden uit Tomodachi Life! (Nintendo 3DS) | 3:32 |
| 149. | Gamekult | 180,707 | Nintendo 2DS : ce qu'il faut savoir | Jeux vidéo par Gamekult | 2:24 |
| 150. | ingwi | 179,380 | *EASY* how to get INFINITE HEARTS in TOMODACHI LIFE - Tomodachi Life (series?) | 4:40 |
| 151. | Kolma | 178,432 | Tomodachi Life - Techno - Nintendo E3 2014 (feat. Hatsune Miku, Kagamine Rin, and Megurine Luka) | 0:53 |
| 152. | Nintendo 公式チャンネル | 171,167 | 『すれちがいMii広場』に4つのあそびが新登場 | 4:44 |
| 153. | Dim Games | 168,186 | tomodachi life cupcakke ft. judge judy - spoiled milk t****** | 1:13 |
| 154. | Ikereviews | 166,264 | sader cutes dream | 0:50 |
| 155. |  TinyLunchboxGamers | 164,916 | Tomodachi Life Song - The Banana | 1:13 |
| 156. | Ricoy | 164,255 | ENCUENTRO un LOOT INCREIBLE GRATIS - RUST - Gameplay español | 18:49 |
| 157. | Tomodachi Life With Rainer and Robert | 161,943 | Sunday Finally Gets To Play Her New Favorite Song Goin’ Down By 3 Days Grace For You Guys | 4:49 |
| 158. |  The Irish Dino | 161,641 | Tomodachi Life: A Philosophy Of Fun | 26:51 |
| 159. | EmSwizzle | 161,369 | WANTED Nintendo Switch Games We WON'T Get... | 0:32 |
| 160. | Big Yellow | 161,252 | Tomodachi Life - The Special Episode Cut | 1:32:30 |
| 161. | ノンケねねし | 160,228 | トモダチコレクション新生活実況 part33【伝説究極ノンケ冒険記】 | 19:12 |
| 162. | Lola's Gamingplace | 158,799 | Eure Fragen zu meinen TomoDachi Life Tricks|Lola's Gaminplace | 5:49 |
| 163. | liss the lass | 158,556 | I finally played Tomodachi Life | 28:07 |
| 164. | GabeRoyale_ | 157,593 | Tomodachi Life is coming to switch. Here’s why. | 8:16 |
| 165. | からすまAチャンネル | 155,916 | ガキ使のクソゲーやりながら年を越す | 1:51:36 |
| 166. |  대도서관TV (buzzbean11) | 155,011 | 담배 몰래피기 게임] 대도서관 코믹 실황 12화 - 흡연 시뮬레이터 (Smoking Simulator) | 32:41 |
| 167. | Jimmy Whetzel | 154,328 | Tomodachi Life Review - Jimmy Whetzel | 4:13 |
| 168. | Nilly896 | 152,112 | Tomodachi Life - Creating 2 Save Datas | 21:11 |
| 169. |  Felipe Bravo | 149,024 | Friend List 3DS (December 23, 2018) | 0:25 |
| 170. | Newtiteuf | 147,700 | [❰❰ REPLAY] Les COMÉDIES MUSICALES sur TOMODACHI ! | 2:00:17 |
| 171. | YuB 2 | 147,577 | sans sings about how much he sucks | 1:14 |
| 172. |  GRAPHIAM | 146,373 | 5 SECRETS sur LES MII | 7:23 |
| 173. | NintendoBelgique | 144,804 | Le show de Mario chat - Épisode 33 | 6:06 |
| 174. | Peebs | 144,232 | NEW SONGS! | Tomodachi Life (Part 3) | 1:40:04 |
| 175. | LinandKoTranslation | 143,217 | Tomodachi Collection : New Life English Subtitled Trailer | 5:32 |
| 176. | Draxr | 141,345 | WHO LIKES ANIME | Tomodachi Life | 54:57 |
| 177. | 우감독 [Director Woo] | 140,462 | 웃소섬에 새 주민 입주시키기★ [우감독 생방송] | 2:52:52 |
| 178. | Nintendo DE | 138,160 | Miitopia: Das große Casting – Trailer (Nintendo 3DS) | 0:48 |
| 179. | みねっと/ MinetteGames | 134,679 | 【トモコレ】4年間で一度も起動しなかったトモコレのデータがヤバいことになっていた【トモダチコレクション 新生活】 | 8:13 |
| 180. | The Sonic Person | 131,753 | The Mine Song but in Tomodachi Life | 0:49 |
| 181. | OctoBoy | 130,693 | LES PERLES DE MIIVERSE 5 | 3:18 |
| 182. |  Swales | 130,466 | GOING DEEP ON TRASH TALKING ROOF CAMPERS - RUST | 24:57 |
| 183. | Humaira Isha | 129,853 | Tomodachi Life box faces (FIXED) | Citra on mac | *WARNING: Please read the pinned comment!!* | 3:40 |
| 184. | こーく-半透明- | 129,235 | トモコレのカメラ機能を使って吉沢亮を作るとこうなる【トモダチコレクション新生活】 | 15:35 |
| 185. | ChilledChaosGAME | 129,177 | A DUMB BLAST FROM THE PAST (Tomodachi Life) | 1:04:07 |
| 186. | Blaine Locklair | 126,413 | NEW! Use This Simple Jailbreak Guide To Hack Your 3DS or 2DS | 27:45 |
| 187. | Retrojeux | 126,182 | Soundhax 3DS et comment installer homebrew launcher et FBI : le tuto ! | 27:11 |
| 188. | Jabroni Mike Full Streams | 125,182 | They Grow Up So Fast - Tomodachi Life | 5:40:44 |
| 189. | Trey Belcastro | 124,548 | Tomodachi Life - Ione will be a kid | 1:22 |
| 190. | Letal | 121,816 | Salve, sono LBN, e questo è il mio canale* | 0:45 |
| 191. |  Csúb - Az Űrmedve | 121,724 | Tomodachi Life a legjobb fan fiction szimulátor | 15:15 |
| 192. | Cheesy Moose | 121,137 | The Sad Truth About Tomodachi Life Switch | 11:00 |
| 193. | NintenDaanNC | 113,397 | [Minna no NC] Tomodachi Collection: New Life - Commercial 3 | 0:30 |
| 194. | Hot Pepper Gaming | 112,731 | Tomodachi Life | Hot Pepper Game Review ft. Michele Morrow | 4:17 |
| 195. | dembonez19 | 110,451 | Tomodachi Life - Extreme Food Reactions | 2:26 |
| 196. |  Rin Penrose Ch. idol-EN | 108,655 | HURRY UP AND HAVE RELATIONSHIP DRAMA ALREADY | 1:23:45 |
| 197. | PIKCAL | 108,378 | LA ANTI-INA | Tomodachi Life Gameplay Español Ep 17 | 22:20 |
| 198. | むーんチャンネル-Moon'sChannel- | 107,852 | #58【ゲームキャラ島/トモダチコレクション新生活】あのゲームキャラたちとケンカして遊んで恋をして‥ 住人募集中!【女性実況】 | 22:31 |
| 199. | smallthoughts | 107,073 | hShop: Should you Download Free Games from the eShop Alternative? | 8:51 |
| 200. | La Poción Roja | 106,904 | Llegó la Muerte de NINTENDO 3DS y Wii U 💀 | 0:59 |
