| Out of the Box (2018) | 1,035,871 | 143 |
| Out of the Park Baseball (1999) | 1,121,154 | 2,506 |
| Out of the Park Baseball 10 (2009) | 0 | 0 |
| Out of the Park Baseball 11 (2010) | 34,176 | 2 |
| Out of the Park Baseball 12 (2011) | 14,804 | 2 |
| Out of the Park Baseball 13 (2012) | 34,614 | 15 |
| Out of the Park Baseball 14 (2013) | 23,695 | 7 |
| Out of the Park Baseball 15 (2014) | 217,980 | 74 |
| Out of the Park Baseball 16 (2015) | 375,120 | 160 |
| Out of the Park Baseball 17 (2016) | 322,332 | 333 |
| Out of the Park Baseball 18 (2017) | 563,488 | 565 |
| Out of the Park Baseball 19 (2018) | 594,214 | 573 |
| Out of the Park Baseball 2 (2000) | 0 | 0 |
| Out of the Park Baseball 20 (2019) | 254,140 | 477 |
| Out of the Park Baseball 21 (2020) | 1,347,147 | 1,782 |
| Out of the Park Baseball 22 (2021) | 1,615,808 | 1,852 |
| Out of the Park Baseball 3 (2001) | 0 | 0 |
| Out of the Park Baseball 4 (2002) | 0 | 0 |
| Out of the Park Baseball 5 (2003) | 0 | 0 |
| Out of the Park Baseball 6 (2004) | 23 | 1 |
| Out of the Park Baseball 6.5 (2005) | 0 | 0 |
| Out of the Park Baseball 8 (2007) | 137 | 1 |
| Out of the Park Baseball 9 (2008) | 0 | 0 |
| Out of the Park Baseball Manager 2006 (2006) | 0 | 0 |
| Out of the Shadows (1984) | 4,417,146 | 459 |
| Out Run (1986) | 16,072,632 | 4,498 |
| Out Run Europa (1991) | 258,589 | 220 |
| Out There (2014) | 185,800,781 | 2,037 |
| Out There Somewhere (2012) | 525,609 | 470 |
| Out There: Oceans of Time (2021) | 1,248,037 | 284 |
| Out to Lunch (1993) | 376,379 | 177 |
| Out Zone (1990) | 458,456 | 366 |
| The Outbound Ghost (2022) | 915,702 | 1,171 |
| Outbreak (2017) | 46,404,802 | 1,634 |
| Outbreak Definitive Collection (2021) | 2,614 | 2 |
| Outbreak The Fedora Files: What Lydia Knows (2024) | 88 | 1 |
| Outbreak: Contagious Memories (2022) | 214,189 | 49 |
| Outbreak: Endless Nightmares (2021) | 425,276 | 301 |
| Outbreak: Epidemic (2020) | 206,143 | 181 |
| Outbreak: Lost Hope (2019) | 89,520 | 125 |
| Outbreak: The New Nightmare (2017) | 101,011 | 67 |
| Outbreak: The New Nightmare (2018) | 417,895 | 204 |
| Outbreak: The Nightmare Chronicles (2018) | 152,867 | 217 |
| Outbuddies (2019) | 216,364 | 160 |
| OUTBUDDIES DX (2019) | 87,448 | 159 |
| Outcast (1999) | 16,757,333 | 4,984 |
| Outcast 1.1 (2014) | 337,020 | 341 |
| The Outcast Lovers (2020) | 1,580 | 27 |
| Outcast: Second Contact (2017) | 3,039,949 | 1,879 |
| Outcasters (2020) | 5,452,009 | 611 |
| Outcore (2022) | 8,154,015 | 517 |
| Outcore: Desktop Adventure (2022) | 513,742 | 123 |
| Outcry (2008) | 874,531 | 216 |
| Outdoor Adventures With Marisa Kirisame (2022) | 2,620 | 7 |
| Outdoors Unleashed: Africa 3D (2011) | 0 | 0 |
| OutDrive (2016) | 478,698 | 121 |
| The Outer Space Bugs (2022) | 215 | 2 |
| Outer Space Shack (2023) | 8,189 | 9 |
| Outer Space: War Gears (2022) | 0 | 0 |
| Outer Wilds (2019) | 120,234,424 | 42,896 |
| The Outer Worlds (2019) | 257,550,237 | 105,121 |
| Outernauts (2012) | 133,158 | 42 |
| Outerstellar (2023) | 71,826 | 43 |
| The Outfit (2006) | 172,556,250 | 7,411 |
| The Outforce (2000) | 5,982 | 16 |
| The Outfoxies (1994) | 646,486 | 317 |
| Outland (2011) | 4,705,932 | 2,301 |
| Outlander (1992) | 429,430 | 183 |
| Outlanders (1987) | 5,936,545 | 896 |
| Outlast (2013) | 2,555,974,745 | 257,517 |
| Outlast 2 (2017) | 293,794,260 | 89,348 |
| Outlast II (2017) | 790,708,575 | 53,004 |
| The Outlast Trials (2022) | 231,121,296 | 44,264 |
| Outlast: Whistleblower (2014) | 204,591,932 | 17,948 |
| Outlaw (1976) | 154,377 | 93 |
