| 1. | Northernlion | Slay the Spire - Northernlion Plays - Episode 1 | 966 | Let's Play |
| 2. | Northernlion | Northernlion Plays Slay the Spire's New Character - Episode 1: The Watcher | 953 | Let's Play |
| 3. | Northernlion | Slay the Spire - Northernlion Plays - Episode 576 [One] | 588 | Let's Play |
| 4. | Northernlion | Slay the Spire - Northernlion Plays - Episode 3 | 511 | Let's Play |
| 5. | Northernlion | Slay the Spire - Northernlion Plays - Episode 29 | 453 | Let's Play |
| 6. | Northernlion | Slay the Spire - Northernlion Plays - Episode 568 [Good Stuff] | 443 | Let's Play |
| 7. | Northernlion | Slay the Spire - Northernlion Plays - Episode 2 | 397 | Let's Play |
| 8. | Northernlion | Slay the Spire - Northernlion Plays - Episode 30 | 348 | Let's Play |
| 9. | Northernlion | Slay the Spire - Northernlion Plays - Episode 105 [Surely Not Another Strength Daily?] | 313 | Let's Play |
| 10. |  Rhapsody | Slay the Spire Draft Champions: On a Rampage - Episode 1 (ft. Olexa) | 308 | Let's Play |
| 11. |  The Brothers Murph | Slay the Spire: The Board Game Playthrough | The Game Haus | 302 | Let's Play |
| 12. | Northernlion | Slay the Spire - Northernlion Plays - Episode 110 [Adrenaline] | 297 | Let's Play |
| 13. | Northernlion | Northernlion Plays Slay the Spire's New Character - Episode 2: Constrict | 285 | Let's Play |
| 14. | ProJared Plays! | IRONCLAD | Slay the Spire #3 | ProJared Plays | 278 | Let's Play |
| 15. | ProJared Plays! | TOP TIER Plays! | Slay the Spire #5 | ProJared Plays | 268 | Let's Play |
| 16. | Northernlion | Slay the Spire - Northernlion Plays - Episode 570 [Eyes] | 266 | Let's Play |
| 17. | Northernlion | Slay the Spire - Northernlion Plays - Episode 111 [Glass] | 239 | Let's Play |
| 18. |  Inside PlayStation | Schwämme, Diebe, Kartentricks: PS+ im April 2022 | 229 | Let's Play |
| 19. | Northernlion | Slay the Spire - Northernlion Plays - Episode 148 [Sweep] | 228 | Let's Play |
| 20. | Rhapsody | Let's Play Slay the Spire: NEW OFFICIAL CHARACTER | The Watcher! - Episode 219 | 224 | Let's Play |
| 21. | Rhapsody | Let's Play Slay the Spire Downfall: Huge Modded Expansion Campaign - Episode 1 | 223 | Let's Play |
| 22. | Northernlion | Slay the Spire - Northernlion Plays - Episode 492 [Chosen] | 222 | Let's Play |
| 23. | Northernlion | Slay the Spire - Northernlion Plays - Episode 533 [Rethink] | 220 | Let's Play |
| 24. | Rhapsody | Let's Play Slay the Spire: Ironclad Ascension Level 20 - Episode 397 | 220 | Let's Play |
| 25. | Northernlion | Slay the Spire - Northernlion Plays - Episode 106 [Salvation] | 219 | Let's Play |
| 26. | Rhapsody | Let's Play Slay the Spire Downfall: Doomsday - Episode 24 | 218 | Let's Play |
| 27. | Northernlion | Slay the Spire - Northernlion Plays - Episode 267 [Plebiscite] | 215 | Let's Play |
| 28. | Northernlion | Slay the Spire - Northernlion Plays - Episode 104 [Could It Be? Another Strength Daily?] | 215 | Let's Play |
| 29. | Northernlion | Northernlion Plays Slay the Spire's New Character - Episode 4: Discount | 202 | Let's Play |
| 30. | Northernlion | Slay the Spire - Northernlion Plays - Episode 109 [Bounty] | 199 | Let's Play |
| 31. | Northernlion | Slay the Spire - Northernlion Plays - Episode 417 [You Wouldn't] | 197 | Let's Play |
| 32. | Northernlion | Slay the Spire - Northernlion Plays - Episode 159 [Flechettes] | 192 | Let's Play |
| 33. | Northernlion | Northernlion Plays Slay the Spire's New Character - Episode 3: Amiss | 192 | Let's Play |
| 34. | Northernlion | Slay the Spire - Northernlion Plays - Episode 420 [Microchip] | 192 | Let's Play |
| 35. | Northernlion | Slay the Spire - Northernlion Plays - Episode 108 [Nightmare] | 191 | Let's Play |
| 36. | Northernlion | Northernlion Plays Slay the Spire's New Character - Episode 26 :Divine | 188 | Let's Play |
| 37. | RageGamingVideos | CRAZY BOSS STRATEGY - HELP ME - Slaying the Spire! (THIS IS INSANE) | 187 | Let's Play |
| 38. | Northernlion | Slay the Spire - Northernlion Plays - Episode 137 [Accuracy] | 186 | Let's Play |
| 39. | Northernlion | Slay the Spire - Northernlion Plays - Episode 114 [Swole] | 185 | Let's Play |
| 40. | Rhapsody | Let's Play Slay the Spire: Full Release - Episode 1 | 183 | Let's Play |
| 41. | Northernlion | Slay the Spire - Northernlion Plays - Episode 562 [Aggression] | 179 | Let's Play |
| 42. | Northernlion | Slay the Spire - Northernlion Plays - Episode 367 [Redemption] | 178 | Let's Play |
| 43. | Northernlion | Slay the Spire - Northernlion Plays - Episode 565 [Bravado] | 177 | Let's Play |
| 44. | Northernlion | Slay the Spire - Northernlion Plays - Episode 157 [Nerf This] | 176 | Let's Play |
| 45. | Rhapsody | Let's Play Slay the Spire: Custom Challenge | Spielen (Play in German w/ Beta Art) - Episode 167 | 174 | Let's Play |
| 46. | Northernlion | Slay the Spire - Northernlion Plays - Episode 174 [Intangible] | 174 | Let's Play |
| 47. | Northernlion | Slay the Spire - Northernlion Plays - Episode 371 [Riposte] | 174 | Let's Play |
| 48. | Rhapsody | Let's Play Slay the Spire: Corrupt Heart | Defect Ascension 20 - Episode 499.999755859375 | 173 | Let's Play |
| 49. | Northernlion | Slay the Spire - Northernlion Plays - Episode 368 [Slammed] | 173 | Let's Play |
| 50. | Northernlion | Slay the Spire - Northernlion Plays - Episode 145 [Innate] | 171 | Let's Play |
| 51. | Northernlion | Slay the Spire - Northernlion Plays - Episode 499 [Minimalism II] | 171 | Let's Play |
| 52. | Northernlion | Slay the Spire - Northernlion Plays - Episode 140 [Doppleganger] | 170 | Let's Play |
| 53. |  ChristopherOdd | Slay The Spire Impressions - AND I'M ADDICTED - 30 Games in 30 Days (7/30) | 170 | Let's Play |
| 54. | Northernlion | Slay the Spire - Northernlion Plays - Episode 369 [Scales] | 169 | Let's Play |
| 55. | Northernlion | Slay the Spire - Northernlion Plays - Episode 151 [Wraith] | 166 | Let's Play |
| 56. | Northernlion | Slay the Spire - Northernlion Plays - Episode 559 [Maybe] | 166 | Let's Play |
| 57. | Northernlion | Northernlion Plays Slay the Spire's New Character - Episode 5: Confusion | 165 | Let's Play |
| 58. | Northernlion | Northernlion Plays Slay the Spire's New Character - Episode 14: Wish | 163 | Let's Play |
| 59. | Northernlion | Slay the Spire - Northernlion Plays - Episode 555 [Dynamic] | 162 | Let's Play |
| 60. | Rhapsody | Let's Play Slay the Spire: Corrupt Heart | Silent Ascension 15 - Episode 495 | 161 | Let's Play |
| 61. | Northernlion | Slay the Spire - Northernlion Plays - Episode 158 [Panache] | 160 | Let's Play |
| 62. | Northernlion | Slay the Spire - Northernlion Plays - Episode 147 [Iron] | 160 | Let's Play |
| 63. | Northernlion | Slay the Spire - Northernlion Plays - Episode 370 [Fireworks] | 160 | Let's Play |
| 64. | Northernlion | Slay the Spire - Northernlion Plays - Episode 126 [Dramatic] | 160 | Let's Play |
| 65. | Northernlion | Northernlion Plays Slay the Spire's New Character - Episode 9: Reliance | 159 | Let's Play |
| 66. | Northernlion | Slay the Spire - Northernlion Plays - Episode 115 [Phantasmal] | 159 | Let's Play |
| 67. | Northernlion | Slay the Spire - Northernlion Plays - Episode 116 [Accursed] | 158 | Let's Play |
| 68. | Rhapsody | Let's Play Slay the Spire Downfall: New Character, The Champ! - Episode 45 | 157 | Let's Play |
| 69. | Rhapsody | Let's Play Slay the Spire Modded: New Character! | Marisa - Episode 82 | 157 | Let's Play |
| 70. | Northernlion | Slay the Spire - Northernlion Plays - Episode 345 [Frigid] | 157 | Let's Play |
| 71. | Northernlion | Slay the Spire - Northernlion Plays - Episode 573 [Curses] | 157 | Let's Play |
| 72. | Northernlion | Slay the Spire - Northernlion Plays - Episode 357 [Invoked] | 155 | Let's Play |
| 73. | Rhapsody | Let's Play Slay the Spire Downfall: New Character, The Automaton! - Episode 52 | 154 | Let's Play |
| 74. | Rhapsody | Let's Play Slay the Spire: Hi! - Episode 267 | 154 | Let's Play |
| 75. | Northernlion | Slay the Spire - Northernlion Plays - Episode 421 [Rain] | 153 | Let's Play |
| 76. | Northernlion | Slay the Spire - Northernlion Plays - Episode 129 [Curses] | 153 | Let's Play |
| 77. | Northernlion | Slay the Spire - Northernlion Plays - Episode 125 [Pommel] | 152 | Let's Play |
| 78. | Northernlion | Northernlion Plays Slay the Spire's New Character - Episode 12: Gotta | 152 | Let's Play |
| 79. | Northernlion | Slay the Spire - Northernlion Plays - Episode 130 [Marathon] | 151 | Let's Play |
| 80. | Rhapsody | Let's Play Slay the Spire Modded: The Mystic - Episode 43 | 151 | Let's Play |
| 81. | ProJared Plays! | TWIN STRIKE | Slay the Spire #4 | ProJared Plays | 151 | Let's Play |
| 82. | Friends Without Benefits | Slay the Spire: Hi Cade - EPISODE 23 - Friends Without Benefits | 150 | Let's Play |
| 83. | Rhapsody | Let's Play Slay the Spire: Endless Mode - Episode 325 | 149 | Let's Play |
| 84. | Northernlion | Slay the Spire - Northernlion Plays - Episode 139 [Bladder] | 149 | Let's Play |
| 85. | Rhapsody | Let's Play Slay the Spire: Defect Ascension Level 14 - Episode 289 | 149 | Let's Play |
| 86. | Rhapsody | Let's Play Slay the Spire: Necroshenanigans - Episode 499.9998779296875 | 149 | Let's Play |
| 87. | Rhapsody | Let's Play Slay the Spire: Custom Challenge | PURE CHAOS (All Modifiers) - Episode 163 | 149 | Let's Play |
| 88. | Rhapsody | Let's Play Slay the Spire Downfall: New Playable Hexaghost Character - Episode 3 | 148 | Let's Play |
| 89. | Northernlion | Slay the Spire - Northernlion Plays - Episode 170 [Dig] | 148 | Let's Play |
| 90. | Northernlion | Slay the Spire - Northernlion Plays - Episode 112 [Flechettes] | 146 | Let's Play |
| 91. | Rhapsody | Let's Play Slay the Spire: NEW CHARACTER (The Defect) Bon Voyage: Episode 232 | 146 | Let's Play |
| 92. | Northernlion | Slay the Spire - Northernlion Plays - Episode 138 [Museum] | 145 | Let's Play |
| 93. | Northernlion | Slay the Spire - Northernlion Plays - Episode 343 [New Content?] | 145 | Let's Play |
| 94. | Rhapsody | Let's Play Slay the Spire Downfall: Taming the Snecko - Episode 4 | 145 | Let's Play |
| 95. | Northernlion | Slay the Spire - Northernlion Plays - Episode 489 [Mood] | 144 | Let's Play |
| 96. | Northernlion | Slay the Spire - Northernlion Plays - Episode 113 [Blur] | 144 | Let's Play |
| 97. | Friends Without Benefits | Slay the Spire: Dillon's Unbridled Rage - EPISODE 43 - Friends Without Benefits | 143 | Let's Play |
| 98. | Northernlion | Northernlion Plays Slay the Spire's New Character - Episode 7: Arithmetic | 143 | Let's Play |
| 99. | Rhapsody | Let's Play Slay the Spire: NEW CHARACTER (The Defect) Energised - Episode 235 | 142 | Let's Play |
| 100. | Northernlion | Slay the Spire - Northernlion Plays - Episode 117 [Shackles] | 142 | Let's Play |
